Figure 1: Patient's thumb protrudes from the clenched fist “Thumb sign” or Steinberg sign” (a). He could easily grip his wrist with overlapping of thumb and little finger of opposite hand “Wrist sign” or “Walker–Murdoch sign” (b). Slit-lamp examination revealed temporosuperior subluxation of lenses with zonular deficiency in both eyes (c). Skin striae on the abdomen of the patients (d).