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Year : 2021  |  Volume : 19  |  Issue : 4  |  Page : 253-257

Febrile neutropenia in the emergency department

1 Department of Pulmonary Medicine, MNR Medical College, Fasalwadi, Telangana, India
2 Department of Emergency Medicine, Christian Medical College, Vellore, Tamil Nadu, India

Correspondence Address:
Dr. Malle Simeon
Department of Pulmonary Medicine, MNR Medical College and Hospital, Fasalwadi, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/cmi.cmi_37_20

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Introduction: Febrile neutropenia is one of the most common presentations to the emergency department. Identification and empirical antibiotic therapy improve the outcome of these patients. The objectives of the study are to collect prospective data on febrile neutropenic patients and describe their clinical profile. Materials and Methods: The study was conducted at the Emergency Department, Christian Medical College and Hospital, Vellore, from July 2017 to February 2018. After obtaining informed consent, all adult patients who presented with fever and neutropenia were included in the study. Results: Of 3778 patients with fever, 101 patients had febrile neutropenia and were included in the study. Males comprised 55.5%. Moderate neutropenia was seen in 30 patients and severe neutropenia was seen in 71 patients. Among the various comorbidities, diabetic patients were more at risk of developing febrile neutropenia (17. 82%). The common organisms isolated were Gram-negative organisms (62. 5%). Coagulase-negative staphylococci and Escherichia coli were the most common organisms. Aplastic anemia was the main diagnosis among those patients with febrile neutropenia (43.76%). The mortality of the febrile neutropenic patients was 1.98%. Overall survival was 96.04%. Conclusion: Empirical antibiotic therapy covering the most common organisms should be started early in febrile neutropenia patients.

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