| REVIEW ARTICLE |
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| Year : 2020 | Volume
: 18
| Issue : 4 | Page : 309-311 |
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Role of tranexamic acid in trauma: Recent updates
Anmol Jindal, Sandeep Nathanael David
Department of Emergency Medicine, Christian Medical College, Vellore, Tamil Nadu, India
Correspondence Address:
Dr. Sandeep Nathanael David
Department of Emergency Medicine, Christian Medical College, Vellore - 632 004, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/cmi.cmi_26_20
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Tranexamic acid (TXA) is a wonder drug in the acute management of hemorrhage in trauma. Recent publication of the CRASH-3 trial results further exemplifies this drug's use in isolated head injury. This article is a review of scientific evidence for TXA in trauma. There is an established role of TXA in trauma with intracranial hemorrhage within 3 h of presentation with 1.5% decrease in mortality of trauma victims with isolated head injury, as per the results of the CRASH-3 trial. However, the optimal dosing and role of the second dose of TXA requires further verification.
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